E2s: structurally economical and functionally replete
نویسندگان
چکیده
منابع مشابه
E2s: structurally economical and functionally replete.
Ubiquitination is a post-translational modification pathway involved in myriad cellular regulation and disease pathways. The Ub (ubiquitin) transfer cascade requires three enzyme activities: a Ub-activating (E1) enzyme, a Ub-conjugating (E2) enzyme, and a Ub ligase (E3). Because the E2 is responsible both for E3 selection and substrate modification, E2s function at the heart of the Ub transfer ...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 2010
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj20100985